Data for: "Boosting understanding of Lassa Fever virus epidemiology: field testing a novel assay to identify past Lassa Fever virus infection in blood and oral fluids of survivors and unexposed controls in Sierra Leone"

Permanent identifier

https://doi.org/10.17037/DATA.00001992

Data description

Quantitative dataset and study tools that underpin the development and validation of a novel Double Antigen Binding Assay identifying anti-Lassa Fever Virus IgG antibodies for the investigation of past infection with Lassa Fever Virus in plasma and oral fluid. Study tools include protocol, questionnaire, consent forms, laboratory information for users, and other details.

Data collection methods

Participants were interviewed face to face using a standardised questionnaire after which oral Fluid and blood samples were collected. Samples were analysed in a laboratory in Sierra Leone by study staff.

Geographic regions

Sierra Leone

Key dates

Data collection performed: May - September 2019
Data submission: 15 December 2020

Privacy

The following actions were performed upon the preservation dataset:

Exact age removed. 5-10 year age group will be used
Exact dates removed.
ID numbers removed and replaced

Keywords

Lassa Fever Virus, Serology, Oral fluid, IgG antibody

Language of written material

English

Project information

Project title	Funder / sponsor	Grant number	Further information
Lassa Oral Fluid Assay Project	DHSC ODA via UK Public Health Rapid Support	RST3_03	https://www.lshtm.ac.uk/research/centres-projects-groups/uk-phrst

Data creators

Forename	Surname	Faculty / Dept	Institution	Role
Hilary	Bower	Faculty of Epidemiology and Population Health / Department of Infectious Disease Epidemiology	London School of Hygiene & Tropical Medicine	Data Creator
Onome	Akpogheneta	Faculty of Infectious and Tropical Diseases	London School of Hygiene & Tropical Medicine	Data Creator
Zainab	Kanneh			Data Creator
Brima	Jusu			Data Creator
Lansana	Kanneh			Data Creator
Foday	Alhasan			Data Creator
Michael	Gbakie			Data Creator
John	Shieffelin		Tulane University	Data Creator

Associated roles

Forename	Surname	Faculty / Dept	Institution	Role
Donald	Grant			Co-investigator
Richard	Tedder		Imperial College London	Co-investigator
Steve	Dicks		Public Health England	Co-investigator
Samreen	Ijaz		Public Health England	Co-investigator
Joseph	Edem-Hotah			Co-investigator

File description

Filename	Description	File format	Access status	Licence
LOFA_dataset	Lassa Fever Oral Fluid ELISA Assay dataset	CSV	Request access	Data sharing agreement
LOFA_dataset_codebook	Codebook for LOFA dataset	HTML	Open	Creative Commons Attribution (CCBY)
LOFA_dataset_userguide	User guide for data collection	HTML	Open	Creative Commons Attribution (CCBY)
Oral_fluid_questionnaires.docx	Eligibility check and questionnaire for survivor and control participants	PDF/A, MS Word .docx	Open	Creative Commons Attribution (CCBY)
Consent-Assent_Form_v2	Participant consent – ascent form	PDF/A	Open	Creative Commons Attribution (CCBY)
Lassa_Oral_Fluid_InfoSheet-LF_survivor	Lassa Virus Survivor Participant Information Sheet	PDF/A	Open	Creative Commons Attribution (CCBY)
Lassa_Oral_Fluid_InfoSheet-unexposed	Lassa Virus Control Participant Information Sheet	PDF/A	Open	Creative Commons Attribution (CCBY)