MAGPIX dataset codebook

Permanent identifier

https://doi.org/10.17037/DATA.00001926

Description

This dataset contains demographic characteristics and laboratory results of 212 study participants who participated in a study on Cervicovaginal immune activation in Zambian women with female genital schistosomiasis. Each row refers to a study participant with a unique study ID number. Data can be shared for the purpose of ethically approved health research, on condition that relevant parties comply with data security conditions and other requirements associated with the research study.

Data access methods

Names and other direct identifiers have been removed prior to submission. Participant age and other information that may be used to identify participants in combination with other data has been placed into broad categories to reduce the disclosure risk. However, there remain a number of unique measurements. Data may only be shared for use in health research, where ethical approval for the work has been obtained.

MAGPIX dataset variables

The following table outlines variables contained within the dataset. However, it may not be feasible to provide access to variables in some circumstances, where there is a recognised disclosure risk. Please list the specific variables that you wish to analyse when requesting data.

Variable name Variable description Variable information Category value Category description
BILID1 Participant study ID (non-linked) study ID number    
agegp4 Age categories. This replaces exact age collected by study How old are you? 1 age 18-24
      2 age 25-31
district study community Is the patient being recruited in community A or Community B    
      1 Community A
      2 Community B
dememp employment status Are you currently working?    
      0 No
      1 Yes
edu3 education What is your level of education?    
      0 No schooling/Any primary school
      1 Any secondary school
      2 Trade/degree/or higher
marst1 marital status What is your marital status?     
      1 Single
      2 Married or living as married
      3 Divorced/separated/widowed
cwateruse childhood water use As a child did you regularly go into (ie swimming, bathing) or use (ie washing, cooking) fresh water outdoors (river, stream, swamp, lake, etc)?    
      0 None
      1 Any
wateruse current water use Do you currently, regularly go into (ie swimming, bathing) or use (ie washing, cooking) fresh water outdoors (river, stream, swamp, lake, etc)?    
      0 None
      1 Any
hadbilz bilharzia status Have you ever been told before that you have had schistosomiasis or bilharzia?    
      0 No
      1 Yes
      2 Maybe - I don't know or I can't remember
everpreg pregnancy status Have you even been pregnant?    
      0 No
      1 Yes
      2 Maybe - I don't know or I can't remember
SBFAGE age at sexual debut How old were you when you first had sex?    
SBNOW sexual activity status Have you been sexually active in the last 6 months?    
      0 No
      1 Yes
      2 Maybe - I don't know or I can't remember
partners lifetime sexual partners How many sexual partners have you had in your lifetime?    
      0 1 lifetime partner
      1 2 lifetime partners
      2 3 lifetime partners
      3 4+ lifetime partners
CONTRAIMP contraceptive use Do you use implants for contraception?    
      0 No
      1 Yes
CONTRAOCP contraceptive use Do you use oral contraceptive tablets for contraception?    
      0 No
      1 Yes
CONTRACON contraceptive use do you use condoms for contraception?    
      0 No
      1 Yes
anyhc1 contraceptive use Study generated variable - use of any of the above contraceptive methods    
      0 No
      1 Yes
HIV-1 hiv status Lab data from the HPTN 071 (PopART) study - HIV status    
      0 Negative
      1 Positive
ctbinary sti status Lab data from the BILHIV study - chlamydia trachomatis status    
      0 Negative
      1 Positive
ngbinary sti status Lab data from the BILHIV study - neisseria gonorrhoaea status    
      0 Negative
      1 Positive
mgbinary sti status Lab data from the BILHIV study - mycoplasma genitalium status    
      0 Negative
      1 Positive
tvbinary sti status Lab data from the BILHIV study - trichomonas vaginalis status    
      0 Negative
      1 Positive
stiany sti status Lab data from the BILHIV study - presence of any sti (ct, ng, mg, tv)    
      0 Negative
      1 Positive
sticks hemoglobin CVL status Lab data from the BILHIV study - presence of any hemoglobin in cervicovaginal lavage by hemasticks    
      0 No erythrocytes detected by hemastick
      1 Trace eyrthrocytes detected by hemastick
      25 25 ery/mL detected by hemastick
      80 80 ery/mL detected by hemastick
      200 200 ery/mL detected by hemastick
fgs1avsp coloposcpy findings Clinic data from the BILHIV study  - did the expert reviewer visualise a cervical lesion consistent with FGS - sandy patch, abnormal vessel, or none?    
      0 No FGS Findings
      1 Sandy Patch
      2 Abnormal blood vessels
Definite1 FGS status Study generated variable - presence of any genital PCR positive (women with probable FGS excluded)    
      0 Negative
      1 Positive
      NULL 25 women with probable FGS are made missing
Probable1 FGS status Study generated variable - presence of probable FGS (women with definite FGS excluded)    
      0 Negative
      1 Positive
      NULL 28 women with definite FGS are made missing
Defprob FGS status Study generated variable - presence of definite or probable FGS    
      0 Negative FGS
      1 Definite or probable FGS
fgscat FGS status Study generate variable - fgs category (negative, probable, definite)    
      0 negative FGS
      1 probable FGS
      2 definite FGS
pcr23pos FGS status Study generated variable - subgroup analysis of women with genital PCR positive (definite FGS), but with 2-3 positive PCR    
      0 negative FGS
      1 pcr for FGS positive and <35ct
      NULL probable fgs and/or women with 1 positive PCR
definite4 FGS status Study generated variable - women with definite FGS, but those with heme positive CVL excluded (sensitivity analysis)    
      0 Negative
      1 Positive
      NULL 147 women with probable FGS or positive heme in CVL are made missing
defhivneg FGS status Study generated variable - women with definite FGS, but those with HIV-1 excluded (sensitivity analysis)    
      0 Negative
      1 Positive
      NULL 56 women with probable FGS or HIV are made missing
mhighct1 FGS status Study generated variable - subgroup analysis of women with genital PCR positive (definite FGS), but with Schistosoma DNA PCR Ct <35    
      0 negative FGS
      1 pcr for FGS positive and <35ct
      NULL probable fgs and/or women with positive PCR and ct>35
logeotaxin eotaxin concentration - measured by MAGPIX log-transformed analyte concentration integer  
logifngamma ifn gamma concentration - measured by MAGPIX log-transformed analyte concentration integer  
logil10 il-10 concentration - measured by MAGPIX log-transformed analyte concentration integer  
logil17a il-17a concentration - measured by MAGPIX log-transformed analyte concentration integer  
logil1a il-1a concentration - measured by MAGPIX log-transformed analyte concentration integer  
logil1b il-1b concentration - measured by MAGPIX log-transformed analyte concentration integer  
logil4 il4 concentration - measured by MAGPIX log-transformed analyte concentration integer  
logil6 il6 concentration - measured by MAGPIX log-transformed analyte concentration integer  
logil8 il8 concentration - measured by MAGPIX log-transformed analyte concentration integer  
logip10 ip10 concentration - measured by MAGPIX log-transformed analyte concentration integer  
logmcp1 mcp1 concentration - measured by MAGPIX log-transformed analyte concentration integer  
logmip1a mip1a concentration - measured by MAGPIX log-transformed analyte concentration integer  
logmip1b mip1b concentration - measured by MAGPIX log-transformed analyte concentration integer  
eotaxincorr eotaxin concentration - measured by MAGPIX analyte concentration corrected for CVL dilution integer  
ifngammacorr ifn gamma concentration - measured by MAGPIX analyte concentration corrected for CVL dilution integer  
il10corr il-10 concentration - measured by MAGPIX analyte concentration corrected for CVL dilution integer  
il17acorr il-17a concentration - measured by MAGPIX analyte concentration corrected for CVL dilution integer  
il1acorr il-1a concentration - measured by MAGPIX analyte concentration corrected for CVL dilution integer  
il1bcorr il-1b concentration - measured by MAGPIX analyte concentration corrected for CVL dilution integer  
il4corr il4 concentration - measured by MAGPIX analyte concentration corrected for CVL dilution integer  
il6corr il6 concentration - measured by MAGPIX analyte concentration corrected for CVL dilution integer  
il8corr il8 concentration - measured by MAGPIX analyte concentration corrected for CVL dilution integer  
ip10corr ip10 concentration - measured by MAGPIX analyte concentration corrected for CVL dilution integer  
mcp1corr mcp1 concentration - measured by MAGPIX analyte concentration corrected for CVL dilution integer  
mip1acorr mip1a concentration - measured by MAGPIX analyte concentration corrected for CVL dilution integer  
mip1bcorr mip1b concentration - measured by MAGPIX analyte concentration corrected for CVL dilution integer  
il5binary presence/absence of il5 - measured by MAGPIX analyte concentration - made binary due to analyte presence in <70% of participants integer  
il13binary presence/absence of il13 - measured by MAGPIX analyte concentration - made binary due to analyte presence in <70% of participants integer  
il15binary presence/absence of il15 - measured by MAGPIX analyte concentration - made binary due to analyte presence in <70% of participants integer  
tnfabinary presence/absence of tnfa - measured by MAGPIX analyte concentration - made binary due to analyte presence in <70% of participants integer