https://doi.org/10.17037/DATA.00001695
Statins are one of the most commonly prescribed drugs in the United Kingdom. There is strong evidence that they are effective in safely reducing heart disease. However, there is some doubt about whether statins cause muscle pain, stiffness or weakness. The StatinWISE study sought to understand the effect of statins on muscle symptoms. The study recruited 200 volunteers from across England and Wales who had either recently stopped taking statins due to muscle symptoms, or were considering stopping due to muscle symptoms.
The Statinwise datasets are made available through an application process. Applicants must outline their proposed research and provide proof of ethical approval for the work.
Variable Name | Variable Label | Answer Label | Answer Code | Variable Type |
share_pid | Unique patient ID for shared data | Open ended | Numeric | |
seq_num | Randomised sequence, numerical version | long | ||
PSPSPS | 1 | |||
PSPSSP | 2 | |||
PSSPPS | 3 | |||
PSSPSP | 4 | |||
SPPSPS | 5 | |||
SPPSSP | 6 | |||
SPSPPS | 7 | |||
SPSPSP | 8 | |||
sex | Sex of participant | long | ||
Female | 1 | |||
Male | 2 | |||
ethnicity | Participant ethnicity | long | ||
Asian | 1 | |||
Black | 2 | |||
Other | 3 | |||
White | 4 | |||
agecat | Categorised participant (years), baseline | Numeric | ||
16-34 | 1 | |||
35-49 | 2 | |||
50-64 | 3 | |||
65-79 | 4 | |||
80+ | 5 | |||
cvd_history | History of cardiovascular disease at baseline | Numeric | ||
No | 0 | |||
Yes | 1 | |||
cvd_angina_chd | Angina/Coronary heart disease (if history of Cardiovascular disease) | Numeric | ||
No | 0 | |||
Yes | 1 | |||
NA | ||||
cvd_mi | Myocardial infarction (if history of Cardiovascular disease) | Numeric | ||
No | 0 | |||
Yes | 1 | |||
NA | ||||
cvd_stroke | Ischameic stroke (if history of Cardiovascular disease) | Numeric | ||
No | 0 | |||
Yes | 1 | |||
NA | ||||
cvd_pvd | Peripheral vascular disease (PVD) (if history of Cardiovascular disease) | Numeric | ||
No | 0 | |||
Yes | 1 | |||
NA | ||||
cvd_other | Other (if history of Cardiovascular disease) | Numeric | ||
No | 0 | |||
Yes | 1 | |||
NA | ||||
systolic | Systolic blood pressure, baseline | Open ended | Integer | |
diastolic | Diastolic blood pressure, baseline | Open ended | Integer | |
use_hbp_meds | Participant uses medication for high blood pressure at baseline | Numeric | ||
No | 0 | |||
Yes | 1 | |||
smoke | Smoking status of participant at baseline | long | ||
Current smoker | 1 | |||
Ex-smoker | 2 | |||
Non-smoker | 3 | |||
cholesterol | Total cholesterol (mmol/L) within 3 years prior to baseline | Open ended | Numeric | |
height | Height (cm), baseline | Open ended | Integer | |
weight | Weight (kg), baseline | Open ended | Integer | |
q_risk | Q-RISK score at baseline (note: some missing values) | Open ended | Numeric | |
diabetes | Participant has diabetes at baseline | Numeric | ||
No | 0 | |||
Yes | 1 | |||
statin_symp_muscle_pain | Symptoms experienced maybe due to statins - muscle pain | Numeric | ||
No | 0 | |||
Yes | 1 | |||
statin_symp_joint_pain | Symptoms experienced maybe due to statins - joint pain | Numeric | ||
No | 0 | |||
Yes | 1 | |||
statin_symp_muscle_weak | Symptoms experienced maybe due to statins - muscle weakness | Numeric | ||
No | 0 | |||
Yes | 1 | |||
statin_symp_fatigue | Symptoms experienced maybe due to statins - fatigue | Numeric | ||
No | 0 | |||
Yes | 1 | |||
statin_symp_nosebleed | Symptoms experienced maybe due to statins - nosebleed | Numeric | ||
No | 0 | |||
Yes | 1 | |||
statin_symp_sore_throat | Symptoms experienced maybe due to statins - sore throat | Numeric | ||
No | 0 | |||
Yes | 1 | |||
statin_symp_digestive | Symptoms experienced maybe due to statins - digestive | Numeric | ||
No | 0 | |||
Yes | 1 | |||
statin_symp_headache | Symptoms experienced maybe due to statins - headache | Numeric | ||
No | 0 | |||
Yes | 1 | |||
statin_symp_nausea | Symptoms experienced maybe due to statins - nausea | Numeric | ||
No | 0 | |||
Yes | 1 | |||
statin_symp_other_cause | Could symptoms experienced on statins have had another cause? | Numeric | ||
No | 0 | |||
Yes | 1 |