Table 1. Sample description: 430 CVD-free participants drawn from the Whitehall II epidemiological cohort between 2006 and 2008 in United Kingdom. Variable,Mean or %,SD Age (years),62.8,5.7 Male (%),55.6, White ethnicity (%),100.0, Smoker (%),4.4, No. of cigarettes per day if smoker,15.0,8.7 Body mass index (Kg/m2),25.7,3.8 Systolic blood pressure (mmHg),128.5,15.3 Diastolic blood pressure (mmHg),69.6,8.4 HDL (mmol/L),1.7,0.5 LDL (mmol/L),3.1,0.8 Total cholesterol (mmol/L),5.4,0.9 Total cholesterol /HDL ratio,3.4,1.0 Glycosylated haemoglobin (mean %),5.4,0.3 Diabetes (%),0.0, Family history of CVD (%),52.7, On treatment for hypertension (%),0.0, On treatment with statins (%),0.0, Rheumatoid arthritis (%),0.0, Estimated risk of CVD events within 10 years (mean %) Framingham,13.2,7.1 JBS/BNF,10.6,6.1 Assign,14.4,7.4 Qrisk2,11.4,5.5 Agatston coronary calcium score (%) None,44.4, < 100,33.7, 100–399,14.2, 400 +,7.7, Detectable HS-CTnT (%),17.9, HS-CTnT concentration if detectable (geom. ng/L),6.0,1.6