https://doi.org/10.17037/DATA.104
An anonymised dataset containing details of a sub-study of 100 HIV-negative women in 2009. This sub-study was part of a microbicide feasibility study in North-West Tanzania that was carried out between 2008-2010. It contains information on sexual behaviour, vaginal practices, current contraception, STI symptoms, as well as results of a clinical and colposcopic examination.
This dataset cannot be made available via a repository due to ethical restrictions. Interested researchers may submit request for de-identified data to Saidi.Kapiga@lshtm.ac.uk.
The dataset produced by the study team contains the variables outlined below.
| Variable name | Variable label | Type | Format | Value label |
| eisno | EIS Study ID | str8 | %9s | |
| visit | Visit (1-12) | float | %9.0g | |
| attend | Attended (y/n) | float | %9.0g | binary |
| labid | LIMS Number | str13 | %13s | |
| visitdate | EIS enrolment date | float | %td | |
| age | Age (v1) | float | %9.0g | |
| healthy | Healthy visit | float | %9.0g | |
| healthytot | Total healthy visits by participant | float | %9.0g | |
| healthyev | Ever had at least one healthy visit | float | %9.0g | |
| menses | Menstruating-pc (v1-v12) | float | %9.0g | |
| totmen | Total menstruations | float | %9.0g | |
| menstage_pdg | Menstrual cycle stage by PDG | float | %16.0g | stage |
| ovulatory | Signs of ovualation? | float | %9.0g | |
| ovulation_study | Was this an ovulatory cycle? | float | %9.0g | |
| fpuse | Contraceptive use (v1) | byte | %8.0g | binary |
| fpcat | Type of contraceptive use (v1) | float | %16.0g | fpcat |
| hc | Hormonal contraception (v1) | float | %9.0g | binary |
| hc_study | Using HC during the study | float | %9.0g | |
| fppill | Oral contraceptive (v1) | byte | %8.0g | binary |
| fpdepo | Depo-Provera (v1) | byte | %8.0g | binary |
| hc3cat_fup | Hormonal contraception category | float | %9.0g | hc3 |
| ivp1 | Cleansing with soap | float | %9.0g | |
| ivp2 | Cleansing with cloth | float | %9.0g | |
| ivp3 | Inserting | float | %9.0g | |
| cleanse_enr | Cleansing - general (v1) | byte | %8.0g | binary |
| cleanse_fu | Cleansing - since last visit (v2-v12) | byte | %8.0g | binary |
| cleanlast | Last time cleanse (v1-v12) | float | %29.0g | cleanlast |
| cleanfreq | Frequency of cleansing (v1-v12) | float | %20.0g | cleanfreq |
| clean_lowhigh | High frequency cleanser (v1-v12) | float | %38.0g | clean_lowhigh |
| water_enr | Cleanse with water - general(v1) | float | %9.0g | binary |
| water_fu | Cleanse with water - since last visit(v2-v12) | float | %9.0g | |
| soap_enr | Cleanse with soap - general(v1) | byte | %8.0g | binary |
| soap_fu | Cleanse with soap - since last visit(v2-v12) | float | %9.0g | |
| fingers_fu | Cleanse with fingers - since last visit (v2-v12) | float | %9.0g | |
| cloth_fu | Cleanse with cloth - since last visit (v2-v12) | byte | %8.0g | binary |
| cotton_fu | Cleanse with cotton - since last visit (v2-v12) | float | %9.0g | |
| appoth_fu | Cleanse with other applicator - since last visit (v2-v12) | float | %9.0g | |
| insert_enr | Inserted a substance - Have you ever? (v1) | float | %9.0g | binary |
| insert_fu | Inserted a substance - since last visit(v2-v12) | byte | %8.0g | binary |
| insert_lowhigh | High freq inserters | float | %9.0g | binary |
| insertfreq | Frequency of inserting (v1-v12) | float | %36.0g | infreq |
| insertsub_fu | What substances have your inserted since last visit TXT (v2-v12) | float | %22.0g | insertsub_f |
| insertlast | Last time insert (v1-v12) | float | %21.0g | inlast |
| sex_fu | Sex since last visit (v2-v12) | byte | %8.0g | binary |
| sexlast | Last sex time (v1-v12) | float | %18.0g | sexlast |
| sex_study | Ever had sex during the study | float | %9.0g | |
| cleanse_study | Ever cleanse during the study | float | %9.0g | |
| soap_study | Ever used soap during the study | float | %9.0g | |
| cloth_study | Ever used cloth during the study | float | %9.0g | |
| insert_study | Ever inserted during the study | float | %9.0g | |
| insertsub_study | Substance inserted during the study | float | %22.0g | insertsub_study |
| vagph | Vaginal pH (v1-v12) | double | %10.0g | |
| phcat | Vaginal pH category | float | %21.0g | phcat |
| cerectopy | Cervical ectopy(v1, v12) | byte | %8.0g | ectopy |
| ectopy | Ectopy - binary | float | %9.0g | |
| ectopy_fu | Cervical ectopy (filled in during f/up) | float | %9.0g | ectopy |
| colvulva | Colposcopic finding: external genitalia (v1, v12) | float | %18.0g | colvulva |
| colvagina | Colposcopic finding: vagina (v1, v12) | float | %27.0g | colvagina |
| colfornix | Colposcopic finding: fornices (v1, v12) | float | %13.0g | colfornix |
| colcervix | Colposcopic finding: cervix (v1, v12) | float | %13.0g | colcervix |
| colfinding | Colposcopic findings | float | %21.0g | colfinding |
| colfind | Any findings on colposcopy | float | %9.0g | |
| psa | Prostate-specific antigen (ng/mL) | float | %9.0g | |
| psa_cat | PSA Semi-qualitative results | float | %24.0g | psa_cat |
| psa_dose | PSA category | float | %12.0g | pdose |
| cvlblood | hemastix testing of supernatant | byte | %23.0g | hemastix |
| menflank | Menstruation & flanking visits | float | %16.0g | menflank |
| leukocytes_lm | Total no. of leukocytes found on LM slides | float | %13.0g | leukocytes_lm |
| lymph_lm | Lymphocytes found on LM slide | float | %9.0g | lymph_lm |
| neutro_lm | Neutrophils found on LM slide | float | %9.0g | neutro_lm |
| prot | Was protein done? | float | %9.0g | binary |
| invol | Was involucrin done? | float | %9.0g | binary |
| il_1alpha | IL-1a | float | %9.0g | |
| il_1beta | IL-1b | float | %9.0g | |
| il_6 | IL-6 | float | %9.0g | |
| il_12 | IL-12 | float | %9.0g | |
| il_18 | IL-18 | float | %9.0g | |
| tnf_alpha | TNF-a | float | %9.0g | |
| il_10 | IL-10 | float | %9.0g | |
| ifn_gamma | Interferon-g | float | %9.0g | |
| il_2 | IL-2 | float | %9.0g | |
| il_4 | IL-4 | float | %9.0g | |
| il_15 | IL-15 | float | %9.0g | |
| il_16 | IL-16 | float | %9.0g | |
| il_17 | IL-17 | double | %10.0g | |
| mip_1alpha | MIP1-a/CCL3 | float | %9.0g | |
| mip_1beta | MIP1-b/CCL4 | float | %9.0g | |
| mcp_1 | MCP-1/CCL2 | float | %9.0g | |
| mcp_2 | MCP-2/CCL8 | float | %9.0g | |
| rantes | RANTES/CCL5 | float | %9.0g | |
| ip_10 | IP-10/CXCL10 | float | %9.0g | |
| sdf_1beta | SDF-1b/CXCL12 | float | %9.0g | |
| mig | MIG/CXCL9 | double | %10.0g | |
| il_8 | IL-8/CXCL8 | float | %9.0g | |
| gm_csf | Granulocyte-macrophage colony-stimulating factor (GM-CSF) | float | %9.0g | |
| g_csf | Granulocyte colony-stimulating factor (G-CSF) | float | %9.0g | |
| tgf_alpha | Transforming growth factor-a (TGF-a) | float | %9.0g | |
| tgf_beta1 | Transforming growth factor-b (TGF-b) | float | %9.0g | |
| ifn_beta | Interferon-b | float | %9.0g | |
| slpi | SLPI | float | %9.0g | |
| elafin | Elafin | float | %9.0g | |
| s100a8 | Calgranulin A (S100A8) | float | %9.0g | |
| hnp_1_3v | Human neutrophil alpha-defensins (HNP) 1-3 | float | %9.0g | |
| b_df2 | Beta-defensin 2 | float | %9.0g | |
| b_df3 | Beta-defensin 3 | float | %9.0g | |
| b_df4 | Beta-defensin 4 | float | %9.0g | |
| pigr | Poly-immunoglobulin receptor | float | %9.0g | |
| iga | Immunoglobulin A | float | %9.0g | |
| igm | Immunoglobulin M | float | %9.0g | |
| igg1 | Immunoglobulin G, subclass 1 | double | %10.0g | |
| igg2 | Immunoglobulin G, subclass 2 | double | %10.0g | |
| igg3 | Immunoglobulin G, subclass 3 | float | %9.0g | |
| igg4 | Immunoglobulin G, subclass 4 | float | %9.0g | |
| apolipoa1 | apolipoa1protein A1 - Serum control | float | %9.0g | |
| scca_1 | SCCA-1 - Vaginal control | float | %9.0g | |
| albumin | Albumin - Serum control | double | %10.0g | |
| involucrin | Involucrin - Vaginal control | float | %9.0g | |
| bradford_assay | Total protein (Bradford assay) | float | %9.0g |