https://doi.org/10.17037/DATA.00001909
Records of human cases of Buruli ulcer collated through literature review and from surveillance programmes by national control programmes. For details on the review methodology, see Simpson et al 2019: Mapping the global distribution of Buruli ulcer: a systematic review with evidence consensus.
The surveillance datasets were compiled through routine surveillance for Buruli ulcer in Cameroon, Ghana, Nigeria and Togo.
Peer-reviewed literature was identified from searches of PubMed and Web of Science databases, updated on 06/08/2018. Additional publications were identified from reference lists of identified papers. We used the search terms (OR): “Buruli ulcer*”, (“Mycob* AND ulcer*”), “Bairnsdale ulcer”. There were no limits on publication date, study type, or location. We included English, French, and Spanish language publications. Publications were eligible for inclusion if they reported geographical locations with evidence of M. ulcerans infection in humans or animals, or detection of M. ulcerans in animal and environmental samples. There were no limits on publication date, participant population, study type or location. Articles that did not report original data were excluded. Studies that recruited patients from health facilities or used strains of M. ulcerans isolated from clinical samples were included in the evidence consensus framework only if patients’ home addresses were provided. Cases with recorded travel history to several endemic regions were excluded. If a dataset was duplicated in numerous papers, the most comprehensive was included.
For full details on literature review methodology, please see Simpson et al. 2019: Mapping the global distribution of Buruli ulcer: a systematic review with evidence consensus. Data contributed by the programme for National Yaws, Leishmaniasis, Leprosy and Buruli ulcer Control Programme in Cameroon are under the ownership of the Ministry of Health in Cameroon and their use is subject to the approval of the Ministry of Health.
This data collection is an update to https://doi.org/10.17037/DATA.00001143.
Occurrences of Mycobacterium ulcerans in animals and environmental samples
| Field name | Description |
| Occurrence_ID | Unique identifier assigned to record in data extratction |
| source_type | Source of record: LIT = literature review, NPR = national programme surveillance data |
| ADM0_NAME | Country name |
| ISO_code3 | Country ISO code |
| ADM1_NAME | First-order administrative divisions name according to GADM https://gadm.org |
| GADM1_ID | First-order administrative divisions ID according to GADM https://gadm.org |
| ADM2_NAME | Second-order administrative divisions name according to GADM https://gadm.org |
| GADM2_ID | Second-order administrative divisions ID according to GADM https://gadm.org |
| Location_name | Name of location given in source |
| lat | latitude of location |
| long | longitude of location |
| Geo_reliability | Reliability of georeferenced location:
|
| max_year | Year of sample as given in source (maximum if range given) |
| N_positive | Number of positive results for location as given in source (maximum if range given) |
| higher_taxon | higher taxon for animal samples |
| lower_taxon | most specific taxonomic level given |
| Sample_type | type of sample: aquatic animal; aquatic non-animal; terrestrial vertebrate- clinical; terrestrial invertebrate; terrestrial vertebrate- faeces; terrestrial vertebrate- clinical; terrestrial non-animal; |
| PCR_Test | PCR target reported |
| ER_result | reported result of PCR targeting endoreticulase gene |
| KR_result | reported result of PCR targeting ketoreductase gene |
| IS2404_result | reported result of PCR targeting insertion sequence 2404 |
| 16SrRNAresults | reported result of PCR targeting 16S RNA sequence |
| 16S_23S ITS | reported result of PCR targeting 16s-23s internal transcribed spacer region |
| IS2606_result | reported result of PCR targeting insertion sequence 2606 |
| VNTR_MIRU_result_MU | reported results of variable nucleotide tandem repeat typing for M. ulcerans |
| VNTR_result_MPM | reported results of variable nucleotide tandem repeat typing for mycolactone producing mycobacteria |
| qPCR_confirmed | reported results of quantitative PCR to confirm M. ulcerans |
| other tests | other tests reported |
| other results | reported results of other tests |
| MU_confirmed | DNA or organism confirmed as M. ulcerans (yes or no) |
Occurrences of Buruli ulcer infections in humans.
| Field name | Description |
| Occurrence_ID | Unique ID for the location record. Point for point locations and Pol for polygon areas |
| source_type | Source type (literature for open access records; author or national programme for restricted access records) |
| reference | Author, year and journal for literature records, data owner for programme records |
| ADM0_NAME | Country name |
| ISO_code3 | Country ISO code |
| ADM1_NAME | Name of upper administrative level from Global Administrative Areas Database |
| GADM1_ID | Upper administrative level ID from Global Administrative Areas Database |
| ADM2_NAME | Name of second administrative level from Global Administrative Areas Database |
| GADM2_ID | Second administrative level ID from Global Administrative Areas Database |
| Location_name | Location name reported in the source |
| lat | Latitude of location (point locations only) |
| long | Longitude of location (point locations only) |
| Geo_reliability | reliability of coordinates: 1 = reported in source; 2 = georeferenced from map provided in source; 3 = remotely georerefenced, exact location identified; 4 = remotely georeferenced, exact location not identified; 5 = nearby location georeferenced |
| max_year | Year of diganosis if reported; most recent year if data spans a range; publication year if year of diagnosis is not reported |
| number | Number of cases reported. 1 if number not reported/ ambiguous |
| Clinical_dxo | Clinical diagnosis reported |
| Ziehl_Neelsen_stain | Ziehl Neelsen test reported |
| ZN_result | Result of Ziehl Neelsen test |
| ZN_n_tested | Number of cases tested by ZN if reported |
| ZN_n_positive | Number of cases positive by ZN if reported |
| ZN_pr_positive | Percentage of cases positive by ZN if reported |
| Culture | Use of culture reported |
| Culture_result | culture result |
| Culture_n_tested | Number of cases tested by culture if reported |
| Culture_n_positive | Number of cases positive by culture if reported |
| Culture_pr_positive | Percentage of cases positive by culture if reported |
| Histo | Use of histopathological analysis reported |
| histo_result | histopathology result |
| histo_n_tested | Number of cases tested by histopathology if reported |
| histo_n_positive | Number of cases positive by histopathology if reported |
| histo_pr_positive | Percentage of cases positive by histopathology if reported |
| PCR_Test | PCR test reported |
| PCR_result | Result of PCR test |
| PCR_n_tested | Number of cases tested by PCR if reported |
| PCR_n_positive | Number of cases positive by PCR if reported |
| PCR_pr_positive | Percentage of cases positive by PCR if reported |
| diagnostic_score | Score for accuracy of diagnosis: PCR or histopathological confirmation = 1; culture and/or ZN confirmation without other confirmatory tests = 0.95; clinical diagnosis alone = 0.5 |
| diagnostic_notes | Notes to assist interpretation of diagnostic score |
Data contributed by the programme for National Yaws, Leishmaniasis, Leprosy and Buruli ulcer Control Programme in Cameroon (contained within 'human_occurrences-NPR') are under the ownership of the Ministry of Health in Cameroon and their use is subject to the approval of the Ministry of Health.
The dataset contains the following values (see above for description)