Doyle, RM, Rubio, M, Dixon, G, Hartley, J, Klein, N, Coll, P and Harris, KA. 2019. Cross-transmission is not the source of new Mycobacterium abscessus infections in a multi-centre cohort of cystic fibrosis patients. [Online]. Clinical Infectious Diseases. Available from: https://doi.org/10.1101/582684
Doyle, RM, Rubio, M, Dixon, G, Hartley, J, Klein, N, Coll, P and Harris, KA. Cross-transmission is not the source of new Mycobacterium abscessus infections in a multi-centre cohort of cystic fibrosis patients. [Internet] LSHTM Data Compass. Clinical Infectious Diseases; 2019. Available from: https://doi.org/10.1101/582684
Doyle, RM, Rubio, M, Dixon, G, Hartley, J, Klein, N, Coll, P and Harris, KA (2019). Cross-transmission is not the source of new Mycobacterium abscessus infections in a multi-centre cohort of cystic fibrosis patients. [Data Collection]. Clinical Infectious Diseases. https://doi.org/10.1101/582684
Description
Mycobacterium abscessus is an extensively drug resistant pathogen that causes pulmonary disease particularly in cystic fibrosis (CF) patients. Identifying direct patient-to-patient transmission of M. abscessus is critically important in directing infection control policy for the management of risk in CF patients. A variety of clinical labs have used molecular epidemiology to investigate transmission. However there is still conflicting evidence as to how M. abscessus is acquired and whether cross-transmission occurs. Recently labs have applied whole-genome sequencing (WGS) to investigate this further and in this study we investigate whether WGS can reliably identify cross-transmission in M. abscessus.
| Data capture method | Experiment |
|---|---|
| Date (Published in a 3rd party system) | 19 June 2019 |
| Language(s) of written materials | English |
| Data Creators | Doyle, RM, Rubio, M, Dixon, G, Hartley, J, Klein, N, Coll, P and Harris, KA |
|---|---|
| Participating Institutions | London School of Hygiene & Tropical Medicine |
| Depositor | Heather Rayner |
|---|---|
| Date Deposited | 22 Jul 2019 10:48 |
| Last Modified | 22 Jul 2019 10:48 |
| Publisher | Clinical Infectious Diseases |
