Low Prevalence of Conjunctival Infection with Chlamydia trachomatis in a Treatment-Naïve Trachoma-Endemic Region of the Solomon Islands

Butcher, RMR, Sokana, O, Jack, K, Macleod, CK, Marks, ME, Kalae, E, Sui, L, Russell, C, Tutill, HJ, Williams, RJ, Breuer, J, Willis, R, Le Mesurier, RT, Mabey, DCW, Solomon, AW and Roberts, Ch. 2016. Low Prevalence of Conjunctival Infection with Chlamydia trachomatis in a Treatment-Naïve Trachoma-Endemic Region of the Solomon Islands. [Online]. Figshare. Available from: https://doi.org/10.1371/journal.pntd.0004863

Butcher, RMR, Sokana, O, Jack, K, Macleod, CK, Marks, ME, Kalae, E, Sui, L, Russell, C, Tutill, HJ, Williams, RJ, Breuer, J, Willis, R, Le Mesurier, RT, Mabey, DCW, Solomon, AW and Roberts, Ch. Low Prevalence of Conjunctival Infection with Chlamydia trachomatis in a Treatment-Naïve Trachoma-Endemic Region of the Solomon Islands [Internet]. Figshare; 2016. Available from: https://doi.org/10.1371/journal.pntd.0004863

Butcher, RMR, Sokana, O, Jack, K, Macleod, CK, Marks, ME, Kalae, E, Sui, L, Russell, C, Tutill, HJ, Williams, RJ, Breuer, J, Willis, R, Le Mesurier, RT, Mabey, DCW, Solomon, AW and Roberts, Ch (2016). Low Prevalence of Conjunctival Infection with Chlamydia trachomatis in a Treatment-Naïve Trachoma-Endemic Region of the Solomon Islands. [Data Collection]. Figshare. https://doi.org/10.1371/journal.pntd.0004863

Description

Description of data capture We conducted a population-based trachoma prevalence survey of 3674 individuals from two Solomon Islands provinces. Participants were examined for clinical signs of trachoma. Conjunctival swabs were collected from all children aged 1–9 years. We tested swabs for Chlamydia trachomatis (Ct) DNA using droplet digital PCR. Chlamydial DNA from positive swabs was enriched and sequenced for use in phylogenetic analysis.
Data capture method Experiment
Data Collection Period
FromTo
October 2013November 2013
Date (Date published in a 3rd party system) 7 September 2016
Geographical area covered (offline during plugin upgrade)
North LatitudeEast LongitudeSouth LatitudeWest Longitude
-9.18141160.823-10.1237159.472
Language(s) of written materials English
Data Creators Butcher, RMR, Sokana, O, Jack, K, Macleod, CK, Marks, ME, Kalae, E, Sui, L, Russell, C, Tutill, HJ, Williams, RJ, Breuer, J, Willis, R, Le Mesurier, RT, Mabey, DCW, Solomon, AW and Roberts, Ch
LSHTM Faculty/Department Faculty of Infectious and Tropical Diseases > Dept of Clinical Research
Participating Institutions London School of Hygiene & Tropical Medicine, London, United Kingdom, Solomon Islands Ministry of Health and Medical Services, Honiara, Solomon Islands, University College London Hospitals, London, United Kingdom, Lata Hospital, Lata, Santa Cruz, Solomon Islands, Bellona Rural Health Centre, Bellona, Solomon Islands, University College London, London, United Kingdom, Task Force for Global Health, Decatur, Georgia, United States of America, Royal Victorian Eye and Ear Hospital, Melbourne, Australia, University of Melbourne, Melbourne, Australia
Funders
ProjectFunderGrant NumberFunder URI
UNSPECIFIEDWellcome Trust098521/B/12/ZUNSPECIFIED
UNSPECIFIEDDepartment for International DevelopmentUNSPECIFIEDUNSPECIFIED
Date Deposited 04 Oct 2016 12:14
Last Modified 27 Apr 2022 18:20
Publisher Figshare

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Filename: S1_Figure.png

Description: Maximum likelihood phylogram of (A) genome and (B) plasmid sequences from clinical specimens assembled using C. trachomatis E/Bour reference. All branches had bootstrap values over 85/100

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Description: Phylogram illustrating relationship of Solomon Islands sequences to reference sequences at (A) ompA, (B) trpA and (C) PZ regions

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Description: This manuscript adheres to the STROBE guidelines

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Description: Sequence accession numbers

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