Supplementary file 2. Intervention repository for DRC outbreaks 
Outbreak	Interventions carried out	Dates (if known)	
1976, Yambuku	Yambuku Mission Hospital closed 	30/10/1976	
	Active surveillance nationwide, in Kinshasa and in the epidemic area		
	A technical note on the disease and practical advice on protection, notification and sample shipping was given to healthcare workers at the national level. Disseminated through radio and the Catholic and Protestant mission amongst others.		
	Isolation of confirmed cases in Kinshasa and quarantine of contacts for 21 days with daily temperature checks		
	Training of local active surveillance teams and provision of protective equipment		
	Involvement of the village chiefs and house-to-house surveying		
	Retrospective surveillance		
	Isolation of cases. Suspected cases were isolated in their village with no close monitoring		
	Barriers installed around villages affected to prevent entry and exit		
	Sodium hypochlorite (2%), boiling or burning were used to decontaminate or dispose of contaminated materials and waste		
	Cadavers wrapped in cloth, soaked in formalin or phenol and buried deeply		
		3	
1995, Kikwit	Closure of all hospitals, health centers and laboratories in the Kikwit area (later reopened)	04/05/1995	
	Quarantine of patients in Kikwit General Hospital		
	Passive surveillance carried out by re-opened healthcare facilities		
	Active surveillance and follow-up carried out by medical students of Bandundu University		
	The establishment of a rumour registry of suspected cases and deaths		
	The use of the Kikwit Diocese radio station and church gatherings for surveillance messages		
	The distribution of protection equipment		
	The infection prevention and control training of medics and other volunteers		
	The organization of safe burials by the Red Cross 		
	Leaflets, posters, banners and speeches through megaphones through the streets of Kikwit		
	Instruction of  approximately 60 healthcare workers on protective equipment, disease characteristics, case definitions and management	12/05/1995 and 14/05/1995	
	Death registry established		
			
2007 Mweka	Retrospective and prospective surveillance		
	Two international mobile laboratories opened, one in Mweka (PHAC) and one in Luebo (CDC)	27/09/2007	
	Organization of safe burials		
	Investigation of drinking water sources and subsequent chlorination of water		
	Disinfection of abandoned households belonging to EVD victims and all major treatment, isolation and healthcare facilities in the area		
	Implementation of protocols for adequate protective equipment, disinfection and hand hygiene amongst healthcare workers		
	Improvement of the general sanitation conditions of the SNCC hospital		
	Construction of three treatment centers, one in Kampungu, one in the Bulape Hospital and one in the Luebo General Hospital and establishment of a transport system for patients		
	Dissemination of knowledge about the disease through leaflets, radio and television education campaigns		
	Provision of free healthcare and food and medical aid for the population residing in the Kampungu area		
	Training of 185 nurses, hygiene technicians and red cross employees		
			
2008/9 Mweka	Arrival of national and international support on site	18/12/2008-25/12/2008	
	Opening of first isolation center by MSF Belgium in Kaluamba	27/12/2008	
	Isolation center was transferred from Kaluamba to Kampungu with 25-bed capacity	02/01/2009	
	Three international mobile laboratories from Canada, Gabon and South Africa were built	15/01/2009	
	The establishment of a surveillance system including contact-tracing using specific forms to be completed for all cases 		
	Health promotion in the community to raise awareness about the disease and how to avert infection (including sessions carried out daily in each village, meetings with authorities from many social groups (eg. priests from many religions, village chiefs, school directors), outreach through songs and messages in local radio stations, at markets and through the distribution of cassettes, response to rumours and household visits) 		
	The symptomatic treatment and isolation of cases to prevent transmission in the community and improve patients’ chances of survival in an environment where appropriate protective equipment and measures were put in place. The interior of the isolation centers were fully visible from the outside to increase transparency with regard to the community. 		
	Burials made safe		
	At-risk households were disinfected		
	Waste was appropriately disposed of 		
	Psychological support was made available to healthcare workers, patients and their families		

2012, Isiro	Laboratory		
	First laboratory was installed, a collaboration between the CDC and the Institut National de Recherche Biomédicale (INRB, Kinshasa)	25/08/2012	
	A team from the PHAC (Winnipeg) arrived and started managing the diagnostic activities together with the INRB. 	 03/10/2012	
	Surveillance		
	Retrospective surveillance (including taking blood samples, consultation of registers, family of cases, community surveys)		
	Prospective surveillance(ensuring healthcare workers use correct definitions, contact tracing and taking blood samples)		
	Creation of a harmonised database that permited real-time epidemiological analysis 		
	Production of a daily bulletin		
	Case management, funeral safety and infection control		
	Isolation unit at the Isiro General Reference Hospital opened	06/08/2012	
	Re-organisation of treatment center at the Isiro General Reference Hospital by MSF Belgium and Spain: isolation units, handwashing stations, waste burning stations	10/08/2012	
	Personal protection equipment distributed		
	Free treatment of patients		
	Systematic (analgesic, antimalarial, antibiotics, vitamins A, B and C) and symptomatic treatments as well as three meals a day were provided		
	The safety of 37 burials was ensured: cadaver disinfected with 0.5% chlorine solution and placed in a bag before funeral and burial. When a death took place at home, the home was disinfected. Sometimes safety of burial was relayed to families and gloves were provided		
	Water, hygiene and sanitation 		
	220 healthcare workers, 34 technicians and 77 red cross employees were trained in disinfection techniques, preparation of chlorine solutions, secure burial and infection control in the healthcare setting. Protection and disinfection equipment was provided.		
	Disinfection of 30 households of cases and 36 healthcare centers		
	Incinerators built by a local engineer and installed in various healthcare centers		
	13 patients were securely transferred 		
	Psychosocial support		
	Psychological support was made available to healthcare workers, patients and their families		
	122 families were provided kits for their reinsertion into the community (bedding, food, bucket, cup and soap)  		
	Psyco-educational sessions in the community and with healthcare workers		
	Social support of families affected (eg. food)		
	400 providers trained in psychological management of EVD cases		
	Communication		
	Briefing of local media, organised groups and community leaders to relay information about EVD		
	Lobbying of political and administrative authorities to gain their support. This resulted in the temporary banning of hunting, playing football and greeting in churches and the use of churches and schools to communicate messages about the disease		
	Flyers, posters, songs in Lingala and other local languages, a radio sketch,  messages transmitted through the Isiro radio stations		
	21 film projections gathering 12,450 people		
	Fast survey of the communication activities	9/10/2012-10/10/2012	
	Register of hostile reactions encountered		
2014, Boende	Evaluation and reinforcement of existing prospective and retrospective surveillance		
	Training of 150 community support workers, 33 community nurses and 52 local healthcare workers		
	Harmonisation of surveillance tools		
	Creation of an a epidemiological surveillance database, a laboratory surveillance database and a treatment centre database		
	Distribution of surveillance tools 		
	21 day follow-up of the contacts of cases		
	Investigation of any alerts (ill or dead individuals)		
	Active search for new cases in the existing healthcare structures (analysis of consultation registers) and in the community (door-to-door knocking in affected villages)		
	Writing and distribution of regular surveillance reports		
	Epidemiological analysis of the outbreak dynamics as it progresses		
	Daily surveillance meetings		
	Set-up of mobile laboratory		
	Case management	Lokolia open 10/09/2014	
	Two Ebola treatment centres subdivided by risk areas. One built from scratch in Lokolia (24 beds) received 40 patients and one in the General Reference Hospital of Boende (18 beds) received 12 patients. Three meals a day provided for patients and their carers		
	Home-based management of one case by a healthcare worker		
	Communication		
	Leaflets and posters in French and Lingala distributed to affected villages and surrounding villages (explained in households for those who spoke only Lomongo)		
	Messages and songs emitted on the local Radio Boende Bosekota		
	Briefing of community representatives (13 village chiefs, 37 healthcare workers, 91 teachers, 61 religious leaders, 3 traditional healers and 43 other community leaders)		
	Door-to-door knocking 		
	Community volunteering for sensibilisation campaigns (122 support workers were trained and given bicycles, megaphones and disinfectants), transfer of patients to the treatment centers and notification of deaths and safe burials.		
	Briefing of affected households		
	Mass speeches in markets, schools and churches		
	Rapid surveys to evaluate the outcome of the sensibilisation campaigns and re-focus efforts		
	Improvement of sanitation and hygiene		
	Supplying protection equipment and disinfectentants to healthcare centers, two schools and the general reference hospital plus briefing on how to use these, hospital hygiene measures and how to dispose of waste		
	Distribution of  soap, water treatment and disinfectants (1200 households), family Wash Kits (25 households) and hand washing buckets (400 households) in the community		
	Disinfection of 521 households, 17 schools, 16 churches and 7 healthcare centers and daily disinfection of Ebola treatment centers		
	Ensuring the safety of 18 burials 		
	Evaluation of water distribution points and supply of drinking water in the meantime		
	Psychosocial support		
	Psychotherapy for healthcare workers, community, EVD cases and their family members (psychoeducational, supportive and community therapies)		
	Nutritional support kits distributed to patients, their families and the local population